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    Week 10B

    Thursday, April 3


    eQTL Mapping and the cis-trans debate

    Download file "Gen660_Lecture10B_eQTL_2014.ppt"

    REQUIRED READING:

    Rockman & Kruglyak. Nat Reviews Gen 2006. Genetics of global gene expression.

    Download file "Rockman_Nature Reviews Genetics_2006.pdf"

    Wittkopp et al. Nat Gen. 2008. Regulatory changes underlying expression differences within and between Drosophila species.

    Download file "Wittkopp_Nat Genet_2008.pdf"


    SUGGESTED READING:

    Brem et al. Science. 2002 Genetic dissection of transcriptional regulation in budding yeast.

    Download file "Brem_Science_2002.pdf"

    Gilad, Rifkin, Pritchard. 2008. Trends in Genetics. Revealing the architecture of gene regulation: the promise of eQTL studies.

    Download file "Gilad_eQTL_TIG_2008.pdf"