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    Week 11B

    Thursday, April 10



    Evolution of cis-regulation - Part I

    Download file "Gen660_Lecture11B_cis-elements_2014.ppt"

    REQUIRED READING:
    Wittkopp & Kalay. Nat Rev Genetics. 2012. Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence.
    Download file "Wittkopp_Kalay_NatRevGen_2012.pdf"

    Ludwig et al. Nature 2000. Evidence for stabilizing selection in a eukaryotic enhancer element.

    Download file "Ludwig_Nature_2000.pdf"