Tags:

    Week 3A

    Tuesday, February 4

    Download file "Gen660_Lecture3A_Ortho-Parology.ppt"

    Orthology, paralogy, and gene history.

    Download file "Carvunis_Nature_2012_protoGenes.pdf"

    REQUIRED READING:

    Koonin. Annu Rev Gen. 2005. Orthologs, Paralogs, and Evolutionary Genomics

    Download file "Koonin_Annu Rev Genet_2005.pdf"

    Brigham et al. 2006. Evolution of hormone-receptor complexity by molecular exploitation.

    Download file "Brigham_Science_2006.pdf"




    SUGGESTED READING:
    Powell et al. 2014. NAR. eggNOG v4.0: nested orthology inference across 3686 organisms.
    Download file "Powell_NAR_2014-eggNOG.pdf"

    Thornton. 2004. Nat Reviews Gen. Resurrecting ancient genes: experimental analysis of extint molecules.

    Download file "thornton-nrg2004b.pdf"

    Finnegan et al. 2012. Nature. Evolution of increased complexity in a molecular machine.

    Download file "Finnigan_Nature2012.pdf"